Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain
نویسندگان
چکیده
منابع مشابه
Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
Cholesterol is implicated to play a role in Alzheimer disease pathology. Therefore, the concentrations of cholesterol, its precursors, and its degradation products in brain homogenates of aging wild-type and beta-amyloid precursor protein transgenic mice carrying the Swedish mutation (APP23) were analyzed. Among the sterols measured, lanosterol is the first common intermediate of two different ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2002
ISSN: 0022-2275
DOI: 10.1194/jlr.m200071-jlr200